Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 14/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2488120 | 1.00 | PTGDR2 (0.50) | PTGDR2TBXA2RLMNAIDO1POLB | |
| SCHEMBL1905325 | 0.93 | PTGDR2 (0.48) | PTGDR2TBXA2R | |
| SCHEMBL2492169 | 0.93 | PTGDR2 (0.48) | PTGDR2TBXA2R | |
| SCHEMBL1905323 | 0.93 | PTGDR2 (0.48) | PTGDR2TBXA2R | |
| SCHEMBL1898557 | 0.92 | PTGDR2 (0.51) | PTGDR2SIGMAR1 | |
| SCHEMBL1898556 | 0.92 | PTGDR2 (0.51) | PTGDR2SIGMAR1 | |
| SCHEMBL1900499 | 0.92 | PTGDR2 (0.51) | PTGDR2SIGMAR1 | |
| SCHEMBL1903879 | 0.92 | PTGDR2 (0.56) | PTGDR2TBXA2RSIGMAR1 | |
| SCHEMBL2487589 | 0.92 | PTGDR2 (0.49) | PTGDR2SIGMAR1 | |
| SCHEMBL2491410 | 0.91 | PTGDR2 (0.50) | PTGDR2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2051962-B1 | (3-AMINO-1,2,3,4-TETRAHYDRO-9H-CARBAZOL-9-YL)-ACETIC ACID DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2011-10-26 | — | — | EP | disclosed |
| EP-2316824-A1 | (3-Amino-1,2,3,4-tetrahydro-9H-carbazoI-9-yl)-acetic acid derivates | Actelion Pharmaceuticals Ltd. (CH) | 2011-05-04 | — | — | EP | disclosed |