Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 10/20 | 0.45 |
| ▸ | AR | P10275 | 9/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL146238 | 0.88 | IDO1 (0.43) | IDO1AR | |
| SCHEMBL19027243 | 0.88 | IDO1 (0.57) | IDO1 | |
| SCHEMBL179729 | 0.87 | IDO1 (0.46) | IDO1AR | |
| SCHEMBL28925350 | 0.87 | IDO1 (0.44) | IDO1AR | |
| SCHEMBL19027424 | 0.86 | IDO1 (0.43) | IDO1AR | |
| SCHEMBL147244 | 0.86 | IDO1 (0.44) | IDO1AR | |
| Iodide SCHEMBL145298 | 0.86 | IDO1 (0.46) | IDO1AR | |
| SCHEMBL30865859 | 0.86 | IDO1 (0.42) | IDO1AR | |
| SCHEMBL19027597 | 0.86 | IDO1 (0.49) | IDO1 | |
| SCHEMBL144829 | 0.86 | IDO1 (0.42) | IDO1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106883193-B | Indoleamine 2,3-dioxygenase inhibitor as well as preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2021-10-15 | — | — | CN | disclosed |
| WO-2017101884-A1 | INDOLAMINE 2,3-DIOXYGENASE INHIBITOR AND PREPARATION METHOD AND USE THEREOF | 江苏豪森药业集团有限公司 | 2017-06-22 | — | — | WO | disclosed |