Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 19/20 | 0.68 |
| ▸ | SPHK1 | Q9NYA1 | 10/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15186367 | 1.00 | SPHK2 (0.68) | SPHK2SPHK1 | |
| SCHEMBL15186523 | 1.00 | SPHK2 (0.68) | SPHK2SPHK1 | |
| SCHEMBL15186370 | 1.00 | SPHK2 (0.68) | SPHK2SPHK1 | |
| Hydrochloric Acid SCHEMBL16933958 | 0.99 | SPHK2 (0.69) | SPHK2SPHK1 | |
| Hydrochloric Acid SCHEMBL16934097 | 0.99 | SPHK2 (0.69) | SPHK2SPHK1 | |
| Hydrochloric Acid SCHEMBL15176558 | 0.99 | SPHK2 (0.69) | SPHK2SPHK1 | |
| Hydrochloric Acid SCHEMBL16933959 | 0.99 | SPHK2 (0.69) | SPHK2SPHK1 | |
| Hydrochloric Acid SCHEMBL15176561 | 0.99 | SPHK2 (0.69) | SPHK2SPHK1 | |
| Hydrochloric Acid SCHEMBL16934099 | 0.99 | SPHK2 (0.69) | SPHK2SPHK1 | |
| SCHEMBL15175875 | 0.85 | SPHK2 (0.51) | SPHK2SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9688668-B2 | Long chain base sphingosine kinase inhibitors | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2017-06-27 | — | — | US | disclosed |
| US-9688668-B2 | Long chain base sphingosine kinase inhibitors | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2017-06-27 | — | — | US | disclosed |