Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 3/20 | 0.39 |
| ▸ | IKBKB | O14920 | 3/20 | 0.39 |
| ▸ | CHUK | O15111 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22025303 | 0.81 | BTK (0.39) | BTKIKBKBHTR2A | |
| SCHEMBL29782477 | 0.79 | BTK (0.60) | BTKIKBKBCHUKCSF1R | |
| SCHEMBL17699797 | 0.79 | BTK (0.60) | BTKIKBKBCHUKCSF1R | |
| SCHEMBL22025054 | 0.74 | BTK (0.73) | BTK | |
| SCHEMBL22025853 | 0.74 | BTK (0.38) | BTK | |
| SCHEMBL11061126 | 0.74 | HTR2A (0.44) | IKBKBHTR2A | |
| Hydrochloric Acid SCHEMBL11065978 | 0.73 | HTR2A (0.43) | HTR2A | |
| SCHEMBL31198719 | 0.67 | HTR2A (0.50) | BTKIKBKBCHUKCSF1RHTR2A | |
| SCHEMBL9310414 | 0.64 | HTR2C (0.65) | IKBKBHTR2A | |
| SCHEMBL22132285 | 0.64 | HTR2C (0.65) | IKBKBHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9688629-B2 | Indole carboxamide compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-06-27 | — | — | US | disclosed |