Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 20/20 | 0.84 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17431751 | 1.00 | FFAR1 (0.84) | FFAR1CYP3A4CYP2C8 | |
| SCHEMBL17428389 | 0.92 | FFAR1 (0.71) | FFAR1CYP3A4CYP2C8 | |
| SCHEMBL17419035 | 0.92 | FFAR1 (1.00) | FFAR1CYP3A4CYP2C8 | |
| SCHEMBL17419132 | 0.92 | FFAR1 (1.00) | FFAR1CYP3A4CYP2C8 | |
| SCHEMBL19035470 | 0.89 | FFAR1 (0.68) | FFAR1CYP3A4CYP2C8 | |
| SCHEMBL17431590 | 0.89 | FFAR1 (0.68) | FFAR1CYP3A4CYP2C8 | |
| SCHEMBL17428386 | 0.84 | FFAR1 (0.84) | FFAR1CYP3A4CYP2C8 | |
| SCHEMBL19035507 | 0.83 | FFAR1 (0.85) | FFAR1CYP3A4CYP2C8 | |
| SCHEMBL17428377 | 0.83 | FFAR1 (0.85) | FFAR1CYP3A4CYP2C8 | |
| SCHEMBL17419160 | 0.82 | FFAR1 (0.70) | FFAR1CYP3A4CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9688642-B2 | Substituted pyrazines as GPR40 agonists | JANSSEN PHARMACEUTICA NV (BE) | 2017-06-27 | — | — | US | disclosed |