Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 20/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17428378 | 1.00 | FFAR1 (0.64) | FFAR1 | |
| SCHEMBL19035506 | 0.91 | FFAR1 (0.64) | FFAR1 | |
| SCHEMBL17428376 | 0.91 | FFAR1 (0.64) | FFAR1 | |
| SCHEMBL17418584 | 0.91 | FFAR1 (0.77) | FFAR1 | |
| SCHEMBL17431775 | 0.89 | FFAR1 (0.52) | FFAR1 | |
| SCHEMBL17428375 | 0.85 | FFAR1 (0.85) | FFAR1 | |
| SCHEMBL19035495 | 0.85 | FFAR1 (0.85) | FFAR1 | |
| SCHEMBL17428379 | 0.85 | FFAR1 (0.85) | FFAR1 | |
| SCHEMBL19035447 | 0.85 | FFAR1 (0.85) | FFAR1 | |
| SCHEMBL17428377 | 0.84 | FFAR1 (0.85) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9688642-B2 | Substituted pyrazines as GPR40 agonists | JANSSEN PHARMACEUTICA NV (BE) | 2017-06-27 | — | — | US | disclosed |