Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | PER2 | O15055 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2145803 | 0.87 | PIK3CD (0.54) | PIK3CDGAATSHRCYP2C19RCE1 | |
| SCHEMBL22548332 | 0.86 | PIK3CD (0.45) | PIK3CDGAATSHRALOX5LMNA | |
| SCHEMBL9684767 | 0.84 | PIK3CD (0.51) | PIK3CDGAATSHRCYP2C19ALOX5 | |
| SCHEMBL9683071 | 0.84 | PIK3CD (0.51) | PIK3CDGAATSHRCYP2C19ALOX5 | |
| SCHEMBL22548335 | 0.83 | PIK3CD (0.42) | PIK3CDGAATSHRALOX5 | |
| SCHEMBL9018974 | 0.82 | PIK3CD (0.51) | PIK3CDGAATSHRCYP2C19RCE1 | |
| SCHEMBL11856423 | 0.81 | PIK3CD (0.47) | PIK3CDGAATSHRCYP2C19RCE1 | |
| SCHEMBL9683077 | 0.80 | GAA (0.46) | PIK3CDGAATSHRALOX5PER2 | |
| SCHEMBL12058905 | 0.79 | PIK3CD (0.66) | PIK3CDGAATSHRCYP2C19RCE1 | |
| SCHEMBL21217031 | 0.79 | PIK3CD (0.61) | PIK3CDGAATSHRCYP2C19RCE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9688669-B2 | Oxazolidinones as modulators of mGluR5 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-06-27 | — | — | US | disclosed |