SCHEMBL190370

SCHEMBL190370

c1ccc(C2CCCCCCC2)cc1

nearest known ligand 0.63

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SLC18A3 Q16572 7/20 0.63
SIGMAR1 Q99720 2/20 0.58
CYP11B2 P19099 1/20 0.56
CYP2D6 P10635 3/20 0.53
KMO O15229 1/20 0.53
CYP2C19 P33261 1/20 0.53
TSHR P16473 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
CYP1A2 P05177 1/20 0.52
CYP2C9 P11712 1/20 0.52
ALDH1A1 P00352 1/20 0.50
APEX1 P27695 1/20 0.50
BLM P54132 1/20 0.50
TRPA1 O75762 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclohexane SCHEMBL11811100 1.00 SLC18A3 (0.63) SLC18A3SIGMAR1CYP11B2CYP2D6KMO
SCHEMBL30731352 1.00 SLC18A3 (0.63) SLC18A3SIGMAR1CYP11B2CYP2D6KMO
Benzene SCHEMBL11808437 1.00 SLC18A3 (0.63) SLC18A3SIGMAR1CYP11B2CYP2D6KMO
SCHEMBL447032 1.00 SLC18A3 (0.63) SLC18A3SIGMAR1CYP11B2CYP2D6KMO
SCHEMBL11562787 1.00 SLC18A3 (0.63) SLC18A3SIGMAR1CYP11B2CYP2D6KMO
SCHEMBL19198566 1.00 SLC18A3 (0.63) SLC18A3SIGMAR1CYP11B2CYP2D6KMO
SCHEMBL790829 1.00 SLC18A3 (0.63) SLC18A3SIGMAR1CYP11B2CYP2D6KMO
SCHEMBL42833 1.00 SLC18A3 (0.63) SLC18A3SIGMAR1CYP11B2CYP2D6KMO
SCHEMBL19262690 1.00 SLC18A3 (0.63) SLC18A3SIGMAR1CYP11B2CYP2D6KMO
Hydrogen Peroxide SCHEMBL11586135 0.97 SLC18A3 (0.61) SLC18A3SIGMAR1CYP11B2CYP2D6KMO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116102478-B Preparation method of 1, 4-dicarbonyl thiosemicarbazide compound and anti-infection application 中国医学科学院药物研究所 2025-04-15 CN claimed
CN-116102478-A Preparation method of 1, 4-dicarbonyl thiosemicarbazide compound and anti-infection application 中国医学科学院药物研究所 2023-05-12 CN claimed
CN-112094535-B Ink formulation, photovoltaic device, and method of making the same 纳晶科技股份有限公司 2022-09-09 CN claimed
CN-112094535-A Ink formulation, photoelectric device and preparation method thereof 纳晶科技股份有限公司 2020-12-18 CN claimed
US-7906686-B2 Process for oxidizing alkylaromatic compounds EXXONMOBIL CHEMICAL PATENTS INC. (US) 2011-03-15 US claimed
US-20100185016-A1 Process for Oxidizing Alkylaromatic Compounds EXXONMOBIL CHEMICAL PATENTS INC. 2010-07-22 US claimed
WO-2008128638-A1 PROCESS FOR OXIDIZING ALKYLAROMATIC COMPOUNDS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2008-10-30 WO claimed
CN-116102478-B Preparation method of 1, 4-dicarbonyl thiosemicarbazide compound and anti-infection application 中国医学科学院药物研究所 2025-04-15 CN disclosed
CN-117957232-A Azaindazole macrocyclic compounds and uses thereof 北京伯汇生物技术有限公司 2024-04-30 CN disclosed
WO-2024051631-A1 MACROCYCLIC IMIDAZO[1,2-B]PYRIDAZINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF 苏州朗睿生物医药有限公司 2024-03-14 WO disclosed
CN-117659043-A Macrocyclic imidazo [1,2-b ] pyridazine derivative and preparation method and application thereof 苏州朗睿生物医药有限公司 2024-03-08 CN disclosed
CN-117586277-A Macrocyclic triazole derivative and preparation method and application thereof 苏州朗睿生物医药有限公司 2024-02-23 CN disclosed
WO-2024032390-A1 MACROCYCLIC TRIAZOLE DERIVATIVE AND PREPARATION METHOD THEREFOR AND USE THEREOF 苏州朗睿生物医药有限公司 2024-02-15 WO disclosed
WO-1994022826-A1 PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1994-10-13 WO disclosed
US-4164617-A Long watertight cable and sleeve joint N.K.F. GROEP B.V. (NL) 1979-08-14 US disclosed
US-4076757-A CROSSLINKING, OXIDATIVE CLEAVAGE TO ACIDS, ALDEHYDES AND ALCOHOLS STUDIENGESELLSCHAFT KOHLE M.B.H. (DT) 1978-02-28 US disclosed
US-4070406-A 1-Phenyl-cyclooctadiene (1,5) STUDIENGESELLSCHAFT KOHLE M.B.H. (DT) 1978-01-24 US disclosed
US-4067918-A CROSSLINKING AGENTS STUDIENGESELLSCHAFT KOHLE M.B.H. (DT) 1978-01-10 US disclosed
US-4056552-A Ethyl 3,7-cyclodecadiene-1-carboxylate STUDIENGESELLSCHAFT KOHLE M.B.H. (DT) 1977-11-01 US disclosed
US-4032585-A CROSSLINKING AGENTS STUDIENGESELLSCHAFT KOHLE M.B.H. (DT) 1977-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100185016-A1 Process for Oxidizing Alkylaromatic Compounds CBR1, AOC3, SCO2 SLC18A3 4064/4885SIGMAR1 373/4885CYP11B2 35/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.