Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PHGDH | O43175 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5140110 | 0.80 | POLB (0.45) | POLBSMN1; SMN2CXCR4HSD17B10KDM4E | |
| SCHEMBL17284646 | 0.80 | POLB (0.45) | POLBSMN1; SMN2CXCR4HSD17B10KDM4E | |
| SCHEMBL237512 | 0.80 | POLB (0.59) | POLBSMN1; SMN2CXCR4HSD17B10ALDH1A1 | |
| SCHEMBL31194975 | 0.78 | POLB (0.43) | POLBSMN1; SMN2CXCR4HSD17B10KDM4E | |
| SCHEMBL28302065 | 0.78 | CXCR4 (0.47) | POLBSMN1; SMN2CXCR4HSD17B10KDM4E | |
| Hydrochloric Acid SCHEMBL17271445 | 0.78 | SMN1; SMN2 (0.43) | POLBSMN1; SMN2CXCR4HSD17B10KDM4E | |
| Hydrochloric Acid SCHEMBL5572604 | 0.77 | POLB (0.56) | POLBSMN1; SMN2CXCR4HSD17B10ALDH1A1 | |
| SCHEMBL9317140 | 0.77 | POLB (0.56) | POLBSMN1; SMN2CXCR4HSD17B10ALDH1A1 | |
| SCHEMBL43582 | 0.77 | CXCR4 (0.61) | POLBSMN1; SMN2CXCR4HSD17B10ALDH1A1 | |
| SCHEMBL14460636 | 0.77 | POLB (0.42) | POLBSMN1; SMN2CXCR4HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7985424-B2 | Dendritic polymers with enhanced amplification and interior functionality | DENDRITIC NANOTECHNOLOGIES INC. (US) | 2011-07-26 | — | — | US | claimed |
| EP-2325236-A1 | Dendritic polymers with enhanced amplification and interior functionality | Dendritic Nanotechnologies Inc. (US) | 2011-05-25 | — | — | EP | claimed |
| US-20070298006-A1 | Dendritic Polymers With Enhanced Amplification and Interior Functionality | DENDRITIC NANOTECHNOLOGIES, INC. (US) | 2007-12-27 | — | — | US | claimed |
| US-7985424-B2 | Dendritic polymers with enhanced amplification and interior functionality | DENDRITIC NANOTECHNOLOGIES INC. (US) | 2011-07-26 | — | — | US | disclosed |
| US-7985424-B2 | Dendritic polymers with enhanced amplification and interior functionality | DENDRITIC NANOTECHNOLOGIES INC. (US) | 2011-07-26 | — | — | US | disclosed |
| US-7985424-B2 | Dendritic polymers with enhanced amplification and interior functionality | DENDRITIC NANOTECHNOLOGIES INC. (US) | 2011-07-26 | — | — | US | disclosed |
| EP-2325236-A1 | Dendritic polymers with enhanced amplification and interior functionality | Dendritic Nanotechnologies Inc. (US) | 2011-05-25 | — | — | EP | disclosed |
| EP-1877103-A2 | DENDRITIC POLYMERS WITH ENHANCED AMPLIFICATION AND INTERIOR FUNCTIONALITY | Dendritic Nanotechnologies, Inc. (US) | 2008-01-16 | — | — | EP | disclosed |
| US-20070298006-A1 | Dendritic Polymers With Enhanced Amplification and Interior Functionality | DENDRITIC NANOTECHNOLOGIES, INC. (US) | 2007-12-27 | — | — | US | disclosed |
| US-20070298006-A1 | Dendritic Polymers With Enhanced Amplification and Interior Functionality | DENDRITIC NANOTECHNOLOGIES, INC. (US) | 2007-12-27 | — | — | US | disclosed |
| US-20070298006-A1 | Dendritic Polymers With Enhanced Amplification and Interior Functionality | DENDRITIC NANOTECHNOLOGIES, INC. (US) | 2007-12-27 | — | — | US | disclosed |
| WO-2006115547-A2 | DENDRITIC POLYMERS WITH ENHANCED AMPLIFICATION AND INTERIOR FUNCTIONALITY | DENDRITIC NANOTECHNOLOGIES, INC. (US) | 2006-11-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070298006-A1 | Dendritic Polymers With Enhanced Amplification and Interior Functionality | MYD88, TLR3, TMEM97 | POLB 73/4885SMN1; SMN2 2102/4885CXCR4 3325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.