SCHEMBL19044151

SCHEMBL19044151

Cc1c(I)ncc2ccncc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CLK1 P49759 1/20 0.41
DYRK1A Q13627 1/20 0.41
TOP2A P11388 1/20 0.37
MAOA P21397 2/20 0.36
HASPIN Q8TF76 2/20 0.36
MAPT P10636 7/20 0.35
KDM4E B2RXH2 3/20 0.34
HTT P42858 2/20 0.34
TNF P01375 1/20 0.34
POLB P06746 1/20 0.34
RAD52 P43351 1/20 0.34
PIM1 P11309 1/20 0.34
LMNA P02545 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
ACHE P22303 1/20 0.33
MAPKAPK2 P49137 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19044150 0.86 KDM4E (0.43) CLK1DYRK1AHASPINKDM4EHTT
SCHEMBL20690963 0.82 CLK1 (0.42) CLK1DYRK1AMAOAHASPINMAPT
SCHEMBL18266932 0.79 CLK1 (0.43) CLK1DYRK1ATOP2AMAOAMAPT
SCHEMBL19044145 0.78 KDM4E (0.47) MAOAMAPTKDM4ELMNACYP1A2
SCHEMBL18848328 0.73 CLK1 (0.42) CLK1DYRK1ATOP2AMAOAHASPIN
SCHEMBL18544822 0.72 CLK1 (0.44) CLK1DYRK1AMAOAHASPINKDM4E
SCHEMBL21297878 0.72 DHODH (0.41) TOP2AMAOAHASPINMAPTKDM4E
SCHEMBL18544875 0.71 HTT (0.44) CLK1DYRK1AHASPINKDM4EHTT
SCHEMBL25307350 0.71 CLK1 (0.47) CLK1DYRK1AMAPTKDM4EHTT
SCHEMBL17532787 0.69 DYRK1A (0.46) CLK1DYRK1ATOP2AMAOAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210257559-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2021-08-19 US disclosed
US-10367147-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2019-07-30 US disclosed
US-10312449-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2019-06-04 US disclosed
US-9793487-B2 2017-10-17 US disclosed
US-20170186975-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-29 US disclosed