Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.49 |
| ▸ | GLS | O94925 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6218596 | 1.00 | NR1H2 (0.61) | NR1H2HPGDKDM4EPKMRECQL | |
| SCHEMBL4729255 | 0.98 | NR1H2 (0.59) | NR1H2HPGDKDM4EPKMRECQL | |
| SCHEMBL27600055 | 0.95 | NR1H2 (0.60) | NR1H2HPGDKDM4EPKMRECQL | |
| SCHEMBL3600795 | 0.94 | HPGD (0.57) | NR1H2HPGDKDM4EPKMRECQL | |
| SCHEMBL372033 | 0.92 | NR1H2 (0.54) | NR1H2HPGDKDM4EPKMRECQL | |
| SCHEMBL31271524 | 0.91 | NR1H2 (0.52) | NR1H2HPGDKDM4EPKMRECQL | |
| SCHEMBL514696 | 0.90 | NR1H2 (0.62) | NR1H2HPGDKDM4EPKMRECQL | |
| SCHEMBL515486 | 0.90 | NR1H2 (0.62) | NR1H2HPGDKDM4EPKMRECQL | |
| SCHEMBL16863978 | 0.90 | NR1H2 (0.58) | NR1H2HPGDKDM4EPKMRECQL | |
| SCHEMBL621267 | 0.90 | NR1H2 (0.62) | NR1H2HPGDKDM4EPKMRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3423 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119684263-A | Synthetic method of terpetinib and key intermediate thereof | 苏州莱安医药化学技术有限公司 | 2025-03-25 | — | — | CN | claimed |
| CN-116462661-A | Deuterated 3- (pyridin-4-yl) propionic acid compound, and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2023-07-21 | — | — | CN | claimed |
| CN-115627505-B | Pulse cyanide-free gold electroplating liquid and electroplating process thereof | 深圳创智芯联科技股份有限公司 | 2023-04-28 | — | — | CN | claimed |
| CN-115627505-A | Pulse cyanide-free gold electroplating solution and electroplating process thereof | 深圳创智芯联科技股份有限公司 | 2023-01-20 | — | — | CN | claimed |
| CN-115557836-A | Preparation method of carboxylic acid | 云南大学 | 2023-01-03 | — | — | CN | claimed |
| CN-110669044-B | Donepezil-oxadiazole fusion compound and preparation method and application thereof | 中国药科大学 | 2022-12-06 | — | — | CN | claimed |
| CN-114874121-A | Method for preparing material containing monothiocarbonate group and product | 浙江大学 | 2022-08-09 | — | — | CN | claimed |
| CN-110669044-A | Donepezil-oxadiazole fusion compound and preparation method and application thereof | 中国药科大学 | 2020-01-10 | — | — | CN | claimed |
| CN-106146459-B | Preparation method of bilastine | 山东罗欣药业集团恒欣药业有限公司 | 2019-12-20 | — | — | CN | claimed |
| US-10457664-B2 | Quinazoline derivatives as VEGF inhibitors | GENZYME CORPORATION (US) | 2019-10-29 | — | — | US | claimed |
| US-20030195230-A1 | Substituted amine derivatives and methods of use | AMGEN INC. | 2003-10-16 | — | — | US | claimed |
| US-20030134836-A1 | Substituted arylamine derivatives and methods of use | AMGEN INC. | 2003-07-17 | — | — | US | claimed |
| US-20030125339-A1 | Substituted alkylamine derivatives and methods of use | AMGEN INC. | 2003-07-03 | — | — | US | claimed |
| WO-2003018019-A2 | NEW USE OF CYCLIC COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-03-06 | — | — | WO | claimed |
| US-20020193405-A1 | Thiazolyl urea compounds and methods of uses | AMGEN INC. | 2002-12-19 | — | — | US | claimed |
| US-20020147198-A1 | Substituted arylamine derivatives and methods of use | AMGEN INC. | 2002-10-10 | — | — | US | claimed |
| WO-2002068406-A2 | SUBSTITUTED AMINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF ANGIOGENESIS | AMGEN INC. (US) | 2002-09-06 | — | — | WO | claimed |
| WO-2002055501-A2 | N-PYRIDYL CARBOXAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AMGEN INC (US) | 2002-07-18 | — | — | WO | claimed |
| EP-1140895-A2 | THIOPYRAN COMPOUNDS AS INHIBITORS OF MMP | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | claimed |
| WO-2000040576-A2 | THIOPYRAN COMPOUNDS AS INHIBITORS OF MMP | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-07-13 | — | — | WO | claimed |