Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | CRHBP | P24387 | 1/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 10/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19002761 | 0.82 | KMT2A (0.57) | KMT2AMEN1CRHBPCRHR2MAPT | |
| SCHEMBL13331971 | 0.77 | GAA (0.55) | KMT2AMEN1MAPTMAPK1RAB9A | |
| SCHEMBL7335661 | 0.77 | MAPT (0.63) | KMT2AMEN1MAPTMAPK1RAB9A | |
| SCHEMBL13528776 | 0.77 | MAPT (0.65) | KMT2AMEN1MAPTMAPK1RAB9A | |
| SCHEMBL7170328 | 0.74 | MAPT (0.57) | KMT2AMEN1MAPTMAPK1RAB9A | |
| SCHEMBL15717116 | 0.73 | GAA (0.53) | KMT2AMEN1MAPTMAPK1RAB9A | |
| SCHEMBL28631373 | 0.73 | MEN1 (0.43) | KMT2AMEN1CRHBPCRHR2MAPT | |
| SCHEMBL17152741 | 0.72 | MAPT (0.50) | KMT2AMEN1MAPTMAPK1RAB9A | |
| SCHEMBL22288574 | 0.72 | MAPT (0.50) | KMT2AMEN1MAPTMAPK1RAB9A | |
| Phosphonic Acid SCHEMBL27298727 | 0.72 | MAPT (0.58) | KMT2AMEN1MAPTMAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017112777-A1 | COMPOUNDS FOR THE TREATMENT OF CANCER AND INFLAMMATORY DISEASE | SHY Therapeutics LLC (US) | 2017-06-29 | — | — | WO | disclosed |