Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | TERT | O14746 | 10/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | RGS12 | O14924 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19052078 | 1.00 | STAT3 (0.50) | STAT3HIF1ATERTMEN1RGS12 | |
| SCHEMBL21726086 | 0.96 | STAT3 (0.47) | STAT3HIF1ATERTMEN1RGS12 | |
| SCHEMBL19052062 | 0.92 | STAT3 (0.44) | STAT3HIF1ATERTMEN1RGS12 | |
| SCHEMBL19052074 | 0.92 | STAT3 (0.44) | STAT3HIF1ATERTMEN1RGS12 | |
| SCHEMBL19052082 | 0.89 | STAT3 (0.41) | STAT3HIF1ATERTMEN1RGS12 | |
| SCHEMBL19052079 | 0.89 | STAT3 (0.41) | STAT3HIF1ATERTMEN1RGS12 | |
| SCHEMBL26495063 | 0.87 | STAT3 (0.55) | STAT3HIF1ATERTMEN1RGS12 | |
| SCHEMBL8071104 | 0.85 | STAT3 (0.65) | STAT3HIF1ATERTMEN1RGS12 | |
| SCHEMBL18379137 | 0.85 | STAT3 (0.65) | STAT3HIF1ATERTMEN1RGS12 | |
| SCHEMBL18376159 | 0.85 | STAT3 (0.65) | STAT3HIF1ATERTMEN1RGS12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170186961-A1 | ORGANIC SEMICONDUCTOR COMPOUNDS AND METHODS OF USE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2017-06-29 | — | — | US | disclosed |