Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19052727 | 0.82 | USP2 (0.33) | CYP1A2USP2ALDH1A1LMNATSHR | |
| SCHEMBL19052718 | 0.82 | USP2 (0.33) | CYP1A2USP2ALDH1A1LMNATSHR | |
| SCHEMBL19029567 | 0.81 | USP2 (0.31) | CYP1A2USP2ALDH1A1LMNATSHR | |
| SCHEMBL19052682 | 0.81 | USP2 (0.31) | CYP1A2USP2ALDH1A1LMNATSHR | |
| SCHEMBL19052824 | 0.81 | USP2 (0.31) | CYP1A2USP2ALDH1A1LMNATSHR | |
| SCHEMBL19029515 | 0.81 | USP2 (0.31) | CYP1A2USP2ALDH1A1LMNATSHR | |
| SCHEMBL19029577 | 0.81 | USP2 (0.33) | CYP1A2USP2ALDH1A1LMNATSHR | |
| SCHEMBL19052676 | 0.81 | USP2 (0.33) | CYP1A2USP2ALDH1A1LMNATSHR | |
| SCHEMBL19052698 | 0.81 | USP2 (0.33) | CYP1A2USP2ALDH1A1LMNATSHR | |
| SCHEMBL19052834 | 0.81 | USP2 (0.33) | CYP1A2USP2ALDH1A1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017107907-A1 | CONDENSED RING Γ-AMINO ACID DERIVATIVE AND PREPARATION METHOD AND MEDICAL USE THEREOF | 四川海思科制药有限公司 | 2017-06-29 | — | — | WO | disclosed |