Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 20/20 | 0.61 |
| ▸ | SCN1A | P35498 | 1/20 | 0.61 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL938085 | 0.84 | SCN5A (0.60) | SCN5ASCN1ASCN2ACYP1A2 | |
| SCHEMBL938385 | 0.84 | SCN5A (0.67) | SCN5ASCN1ASCN2ACYP1A2 | |
| SCHEMBL937229 | 0.83 | SCN5A (0.66) | SCN5ASCN1ASCN2ACYP1A2 | |
| SCHEMBL937029 | 0.80 | SCN5A (0.65) | SCN5ASCN1ASCN2ACYP1A2 | |
| SCHEMBL937623 | 0.79 | SCN5A (0.63) | SCN5ASCN1ASCN2ACYP1A2 | |
| SCHEMBL938458 | 0.78 | SCN5A (0.60) | SCN5ASCN1ASCN2ACYP1A2 | |
| SCHEMBL937063 | 0.78 | SCN5A (0.66) | SCN5ASCN1ASCN2ACYP1A2 | |
| SCHEMBL938049 | 0.78 | SCN5A (0.53) | SCN5ASCN1ASCN2ACYP1A2 | |
| SCHEMBL936953 | 0.78 | SCN5A (0.65) | SCN5ASCN1ASCN2ACYP1A2 | |
| SCHEMBL936844 | 0.78 | SCN5A (0.65) | SCN5ASCN1ASCN2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2464645-B1 | FUSED HETEROCYCLIC COMPOUNDS AS ION CHANNEL MODULATORS | GILEAD SCIENCES INC (US) | 2017-07-05 | — | — | EP | claimed |