Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL189379 | 0.81 | CA12 (0.51) | SMN1; SMN2RAB9AMAPTL3MBTL1NPC1 | |
| SCHEMBL189579 | 0.78 | SMN1; SMN2 (0.50) | SMN1; SMN2RAB9AMAPTL3MBTL1NPC1 | |
| SCHEMBL189902 | 0.77 | SMN1; SMN2 (0.48) | SMN1; SMN2RAB9AMAPTL3MBTL1NPC1 | |
| SCHEMBL190352 | 0.77 | SMPD1 (0.48) | SMN1; SMN2RAB9AMAPTL3MBTL1NPC1 | |
| SCHEMBL189402 | 0.76 | SMN1; SMN2 (0.47) | SMN1; SMN2RAB9AMAPTL3MBTL1NPC1 | |
| SCHEMBL190629 | 0.76 | SMN1; SMN2 (0.50) | SMN1; SMN2RAB9AMAPTL3MBTL1NPC1 | |
| SCHEMBL190253 | 0.76 | SMN1; SMN2 (0.49) | SMN1; SMN2RAB9AMAPTL3MBTL1NPC1 | |
| SCHEMBL189578 | 0.76 | SMN1; SMN2 (0.49) | SMN1; SMN2RAB9AMAPTL3MBTL1NPC1 | |
| SCHEMBL189585 | 0.76 | SMPD1 (0.47) | SMN1; SMN2RAB9AMAPTL3MBTL1NPC1 | |
| Hydrochloric Acid SCHEMBL189401 | 0.75 | SMN1; SMN2 (0.46) | SMN1; SMN2RAB9AMAPTL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401263-A2 | SUBSTITUTED AZOLE DERIVATIVES, PHARMACEUTICAL COMPOSITION CONTAINING THE DERIVATIVES, AND METHOD FOR TREATING PARKINSON'S DISEASE USING THE SAME | SK Biopharmaceuticals Co., Ltd. (KR) | 2012-01-04 | — | — | EP | disclosed |