Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | USP1 | O94782 | 1/20 | 0.30 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL391957 | 0.87 | CYP1A2 (0.38) | CYP1A2MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL391847 | 0.86 | CYP1A2 (0.40) | CYP1A2MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL1904848 | 0.73 | CYP1A2 (0.36) | CYP1A2MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL3691975 | 0.69 | CYP1A2 (0.50) | CYP1A2MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL14403201 | 0.65 | CYP1A2 (0.51) | CYP1A2MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL392408 | 0.64 | CYP1A2 (0.54) | CYP1A2MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL8377531 | 0.62 | CYP1A2 (0.56) | CYP1A2MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL391954 | 0.60 | CYP1A2 (0.85) | CYP1A2MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL390010 | 0.59 | CYP1A2 (0.53) | CYP1A2 | |
| SCHEMBL386861 | 0.57 | CYP1A2 (0.60) | CYP1A2MEN1ALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2322157-A1 | Composition for the treatment of diabetes and conditions related thereto and for the treatment of conditions ameliorated by increasing a blood GLP-1 level | Arena Pharmaceuticals, Inc. (US) | 2011-05-18 | — | — | EP | disclosed |