SCHEMBL19061284 — predicted protein targets

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	PDK2	Q15119	2/20	0.40

▸	CYP1A2	P05177	3/20	0.39

▸	METAP2	P50579	3/20	0.39

▸	MDM2	Q00987	1/20	0.38

▸	MAT2A	P31153	6/20	0.35

▸	CYP11B2	P19099	2/20	0.34

▸	ALOX12	P18054	1/20	0.34

▸	CYP11B1	P15538	1/20	0.34

▸	PRMT5	O14744	1/20	0.34

▸	GSK3B	P49841	2/20	0.34

▸	GFER	P55789	1/20	0.34

▸	NPSR1	Q6W5P4	1/20	0.34

▸	PRKCB	P05771	1/20	0.34

▸	PRKCA	P17252	1/20	0.34

▸	HTT	P42858	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL19061501	0.96	PDK2 (0.41)	PDK2CYP1A2METAP2MDM2MAT2A
SCHEMBL19061533	0.96	CYP1A2 (0.39)	PDK2CYP1A2METAP2MDM2MAT2A
SCHEMBL19061240	0.94	PDK2 (0.40)	PDK2CYP1A2METAP2MDM2CYP11B2
SCHEMBL19061232	0.90	PDK2 (0.41)	PDK2CYP1A2METAP2MDM2CYP11B2
SCHEMBL19061337	0.90	PDK2 (0.39)	PDK2CYP1A2METAP2MDM2CYP11B2
SCHEMBL19061802	0.89	CYP1A2 (0.39)	PDK2CYP1A2METAP2MDM2MAT2A
SCHEMBL17427720	0.88	CYP1A2 (0.38)	PDK2CYP1A2METAP2MDM2MAT2A
SCHEMBL19061272	0.88	KDM4E (0.45)	PDK2
SCHEMBL802605	0.87	CYP1A2 (0.40)	CYP1A2METAP2MDM2MAT2ACYP11B2
SCHEMBL2603500	0.87	CYP1A2 (0.40)	CYP1A2METAP2MDM2MAT2ACYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2017111389-A1	ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DIODE INCLUDING SAME	주식회사 두산	2017-06-29	—	—	WO	disclosed