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SCHEMBL19061335

SCHEMBL19061335

CC1(C)c2ccccc2-c2ccc(-c3ccc(-c4cccc5c6ccccc6n(-c6cccc(-c7nc(-c8ccccc8)nc(-c8ccc(-c9ccccc9)cc8)n7)c6)c45)cc3)cc21

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ PDE10A Q9Y233 1/20 0.33
▸ PDK2 Q15119 4/20 0.33
▸ DUSP3 P51452 1/20 0.32
▸ KDM4E B2RXH2 1/20 0.30
▸ ATM Q13315 1/20 0.30
▸ L3MBTL1 Q9Y468 1/20 0.30
▸ ALDH1A1 P00352 1/20 0.30
▸ LMNA P02545 1/20 0.30
▸ GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19061326 1.00 PDE10A (0.33) PDE10APDK2DUSP3KDM4EATM
SCHEMBL19061322 0.97 PDE10A (0.33) PDE10APDK2DUSP3
SCHEMBL19061313 0.96 DUSP3 (0.32) PDE10APDK2DUSP3KDM4EATM
SCHEMBL19061691 0.95 PDE10A (0.33) PDE10APDK2DUSP3KDM4EL3MBTL1
SCHEMBL19061690 0.94 PDK2 (0.34) PDK2DUSP3KDM4EATML3MBTL1
SCHEMBL19061344 0.94 PDK2 (0.34) PDK2DUSP3KDM4EATML3MBTL1
SCHEMBL19061339 0.94 PDK2 (0.34) PDK2DUSP3KDM4EATML3MBTL1
SCHEMBL19061329 0.94 PDK2 (0.36) PDE10APDK2DUSP3KDM4EATM
SCHEMBL24216703 0.93 PDE10A (0.32) PDE10APDK2DUSP3
SCHEMBL24959921 0.93 PDE10A (0.32) PDE10APDK2DUSP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017111389-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DIODE INCLUDING SAME 주식회사 두산 2017-06-29 — — WO disclosed
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