Oxirane

Oxirane

SCHEMBL1906259

C1CO1.CC(C)(C)C=CC(=O)O

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.36
TP53 P04637 1/20 0.36
EGLN1 Q9GZT9 1/20 0.36
EGLN3 Q9H6Z9 1/20 0.36
USP2 O75604 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HCAR2 Q8TDS4 1/20 0.31
GABRP O00591 2/20 0.30
GABRD O14764 2/20 0.30
GABRA1 P14867 2/20 0.30
GABRB1 P18505 2/20 0.30
GABRG2 P18507 2/20 0.30
GABRB3 P28472 2/20 0.30
GABRA5 P31644 2/20 0.30
GABRA3 P34903 2/20 0.30
GABRA2 P47869 2/20 0.30
GABRB2 P47870 2/20 0.30
GABRA4 P48169 2/20 0.30
GABRE P78334 2/20 0.30
GABRA6 Q16445 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL319288 0.87
SCHEMBL179976 0.87
Butadiene SCHEMBL1172510 0.80 TSHR (0.40) TSHRTP53EGLN1EGLN3HCAR2
Fumaric Acid SCHEMBL28230141 0.76 TSHR (0.64) TSHRTP53EGLN1EGLN3SMN1; SMN2
Maleic Acid SCHEMBL7183468 0.76 TSHR (0.64) TSHRTP53EGLN1EGLN3SMN1; SMN2
Fumaric Acid SCHEMBL7183473 0.76 TSHR (0.64) TSHRTP53EGLN1EGLN3SMN1; SMN2
Glycine SCHEMBL5168496 0.74 GLRA1 (0.46) TSHRTP53EGLN1EGLN3HCAR2
Methacrylic Acid SCHEMBL5169381 0.74 TSHR (0.35) TSHRTP53EGLN1EGLN3HCAR2
Maleic Acid SCHEMBL28102294 0.73 TSHR (0.60) TSHRTP53EGLN1EGLN3SMN1; SMN2
SCHEMBL6469047 0.73 TSHR (0.33) TSHRTP53EGLN1EGLN3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160161475-A1 HYBRID SEMICONDUCTING POLYMER NANOPARTICLES AS POLARIZATION-SENSITIVE FLUORESCENT PROBES UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION 2016-06-09 US claimed
EP-3019443-A1 HYBRID SEMICONDUCTING POLYMER NANOPARTICLES AS POLARIZATION SENSITIVE FLUORESCENT PROBES University Of Washington Through Its Center For Commercialization (US) 2016-05-18 EP claimed
US-20160018405-A1 METHODS AND SYSTEMS FOR ANALYSIS USING POLYMER DOTS University of Washington Through it's Center for Commercialization (US) 2016-01-21 US claimed
EP-2653867-A1 Biotracer and its use in an immunoassay King Saud University (SA) 2013-10-23 EP claimed
EP-3277846-B1 OPTICAL PAINTING AND FLUORESCENCE-ACTIVATED SORTING OF ADHERENT CELLS UNIV WASHINGTON (US) 2024-07-10 EP disclosed
US-20240069032-A1 FUNCTIONALIZED CHROMOPHORIC POLYMER DOTS AND BIOCONJUGATES THEREOF CLEMSON UNIVERSITY RESEARCH FOUNDATION 2024-02-29 US disclosed
US-20230408526-A1 CHROMOPHORIC POLYMER DOTS UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) 2023-12-21 US disclosed
US-11835526-B2 Functionalized chromophoric polymer dots and bioconjugates thereof UNIVERSITY OF WASHINGTON (US) 2023-12-05 US disclosed
US-11753681-B2 Digital nucleic acid amplification using encoded particles UNIVERSITY OF WASHINGTON (US) 2023-09-12 US disclosed
US-11674964-B2 Encoded chromophoric polymer particles and methods of use thereof UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) 2023-06-13 US disclosed
US-20230159979-A1 TRANSDUCERS, NANOPARTICLE TRANSDUCER DEVICES AND SYSTEMS, AND RELATED METHODS OF USE UNIVERSITY OF WASHINGTON (US) 2023-05-25 US disclosed
US-20230077385-A1 NANOPARTICLE TRANSDUCER SENSORS AND METHODS OF USE THEREOF UNIVERSITY OF WASHINGTON (US) 2023-03-16 US disclosed
WO-2012054525-A2 CHROMOPHORIC POLYMER DOTS University of Washington Center for Commercialization (US) 2012-04-26 WO disclosed
WO-2011057295-A2 FUNCTIONALIZED CHROMOPHORIC POLYMER DOTS AND BIOCONJUGATES THEREOF University of Washington Center for Commercialization (US) 2011-05-12 WO disclosed
US-7846412-B2 Nanoparticle fluorescent probes comprised of quantum dot and hydrophobic protection structure including capping ligand and amphiphilic copolymer; biocompatibility; multiplexed imaging and detection of genes and proteins in single living cells; cancer diagnosis EMORY UNIVERSITY (US) 2010-12-07 US disclosed
WO-2008137733-A2 MICELLAR STRUCTURES, METHODS OF MAKING MICELLAR STRUCTURES, METHODS OF IMAGING, AND METHODS OF DELIVERING AGENTS EMORY UNIVERSITY (US) 2008-11-13 WO disclosed
WO-2008116044-A1 SEMICONDUCTOR QUANTUM DOTS FOR EFEICIENT DELIVERY AND INTRACELLULAR IMAGING OF SIRNA EMORY UNIVERSITY (US) 2008-09-25 WO disclosed
EP-1696784-A2 BIOCONJUGATED NANOSTRUCTURES, METHODS OF FABRICATION THEREOF, AND METHODS OF USE THEREOF Emory University (US) 2006-09-06 EP disclosed
WO-2005065081-A2 BIOCONJUGATED NANOSTRUCTURES, METHODS OF FABRICATION THEREOF, AND METHODS OF USE THEREOF EMORY UNIVERSITY (US) 2005-07-21 WO disclosed
US-20050136258-A1 Nanoparticle fluorescent probes comprised of quantum dot and hydrophobic protection structure including capping ligand and amphiphilic copolymer; biocompatibility; multiplexed imaging and detection of genes and proteins in single living cells; cancer diagnosis NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2005-06-23 US disclosed