Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANO1 | Q5XXA6 | 19/20 | 0.56 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1952323 | 0.82 | ANO1 (0.61) | ANO1ANO2MEN1KMT2A | |
| SCHEMBL1905629 | 0.79 | ANO1 (0.60) | ANO1ANO2MEN1KMT2A | |
| SCHEMBL1907122 | 0.79 | ANO1 (0.60) | ANO1ANO2MEN1KMT2A | |
| SCHEMBL1954662 | 0.77 | ANO1 (0.63) | ANO1ANO2MEN1KMT2A | |
| SCHEMBL1954508 | 0.77 | ANO1 (0.57) | ANO1ANO2MEN1KMT2A | |
| SCHEMBL1954070 | 0.75 | ANO1 (0.61) | ANO1ANO2MEN1KMT2A | |
| SCHEMBL1954102 | 0.75 | ANO1 (0.61) | ANO1ANO2MEN1KMT2A | |
| SCHEMBL12271278 | 0.75 | ANO1 (0.80) | ANO1ANO2MEN1KMT2A | |
| SCHEMBL1954635 | 0.74 | ANO1 (0.60) | ANO1ANO2MEN1KMT2A | |
| SCHEMBL1894210 | 0.74 | ANO1 (0.51) | ANO1ANO2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2321303-A2 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | Calcimedica, Inc. (US) | 2011-05-18 | — | — | EP | disclosed |
| WO-2010027875-A2 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA INC. (US) | 2010-03-11 | — | — | WO | disclosed |