SCHEMBL19066479

SCHEMBL19066479

CCOc1ccc(-c2ccc(C3(O)CCC(C)(CC)CC3)cc2F)cc1F

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 2/20 0.39
AKR1C2 P52895 2/20 0.39
AKR1B10 O60218 1/20 0.39
AKR1C4 P17516 1/20 0.39
AKR1C1 Q04828 1/20 0.39
APP P05067 8/20 0.38
CYP2C19 P33261 6/20 0.38
CYP2C9 P11712 6/20 0.38
CYP3A4 P08684 5/20 0.38
SSTR5 P35346 1/20 0.38
NAAA Q02083 1/20 0.35
KDM1A O60341 2/20 0.35
RARG P13631 1/20 0.35
PSEN1 P49768 1/20 0.34
PSEN2 P49810 1/20 0.34
APH1B Q8WW43 1/20 0.34
NCSTN Q92542 1/20 0.34
APH1A Q96BI3 1/20 0.34
PSENEN Q9NZ42 1/20 0.34
FAAH O00519 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19090346 0.81 SSTR5 (0.40) SSTR5
SCHEMBL22161982 0.73 SSTR5 (0.41) CYP3A4SSTR5NAAAKDM1AFAAH
SCHEMBL19066520 0.73 SSTR5 (0.39) SSTR5
SCHEMBL19090166 0.72 SSTR5 (0.41) APPCYP2C19CYP2C9CYP3A4SSTR5
SCHEMBL19090168 0.71 SSTR5 (0.41) SSTR5
SCHEMBL19066513 0.70 SSTR5 (0.37) SSTR5
SCHEMBL8932623 0.70 APP (0.35) AKR1C3AKR1C2AKR1B10AKR1C4AKR1C1
SCHEMBL22622836 0.70 KDM1A (0.42) CYP3A4SSTR5NAAAKDM1AFAAH
SCHEMBL16855917 0.69 FGFR2 (0.46) NAAAKDM1AFAAHPTGS2
SCHEMBL19066491 0.69 SSTR5 (0.39) SSTR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017116213-A1 LIQUID CRYSTAL COMPOUND AND LIQUID CRYSTAL COMPOSITION CONTAINING SAME 주식회사 동진쎄미켐 2017-07-06 WO disclosed