Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 8/20 | 0.58 |
| ▸ | ADH1B | P00325 | 2/20 | 0.58 |
| ▸ | ADH1C | P00326 | 2/20 | 0.58 |
| ▸ | ADH1A | P07327 | 2/20 | 0.58 |
| ▸ | ADH7 | P40394 | 2/20 | 0.58 |
| ▸ | ADH4 | P08319 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.38 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | GBA1 | P04062 | 2/20 | 0.35 |
| ▸ | CASP2 | P42575 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22157385 | 1.00 | EPHX1 (0.58) | EPHX1ADH1BADH1CADH1AADH7 | |
| SCHEMBL22157384 | 1.00 | EPHX1 (0.58) | EPHX1ADH1BADH1CADH1AADH7 | |
| SCHEMBL10350548 | 1.00 | EPHX1 (0.58) | EPHX1ADH1BADH1CADH1AADH7 | |
| SCHEMBL11859016 | 1.00 | EPHX1 (0.58) | EPHX1ADH1BADH1CADH1AADH7 | |
| SCHEMBL11859005 | 1.00 | EPHX1 (0.58) | EPHX1ADH1BADH1CADH1AADH7 | |
| SCHEMBL16452855 | 1.00 | EPHX1 (0.58) | EPHX1ADH1BADH1CADH1AADH7 | |
| Ammonia Solution, Strong SCHEMBL10827255 | 0.98 | EPHX1 (0.56) | EPHX1ADH1BADH1CADH1AADH7 | |
| Ammonia Solution, Strong SCHEMBL10827263 | 0.98 | EPHX1 (0.56) | EPHX1ADH1BADH1CADH1AADH7 | |
| Ammonia Solution, Strong SCHEMBL10826393 | 0.98 | EPHX1 (0.56) | EPHX1ADH1BADH1CADH1AADH7 | |
| Ammonia Solution, Strong SCHEMBL7039907 | 0.98 | EPHX1 (0.56) | EPHX1ADH1BADH1CADH1AADH7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020190754-A1 | MACROCYCLIC AZOLOPYRIDINE DERIVATIVES AS EED AND PRC2 MODULATORS | Fulcrum Therapeutics, Inc. (US) | 2020-09-24 | — | — | WO | disclosed |
| WO-2017201342-A1 | POLYNUCLEOTIDES ENCODING JAGGED1 FOR THE TREATMENT OF ALAGILLE SYNDROME | MODERNATX, INC. (US) | 2017-11-23 | — | — | WO | disclosed |
| US-9695368-B2 | Process and apparatus employing microchannel process technology | VELOCYS, INC. (US) | 2017-07-04 | — | — | US | disclosed |