Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Silver. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Silver SCHEMBL664567 | 0.87 | — | — | |
| Silver SCHEMBL18123635 | 0.87 | — | — | |
| SCHEMBL8333713 | 0.82 | — | — | |
| SCHEMBL8333775 | 0.82 | — | — | |
| SCHEMBL7457068 | 0.82 | — | — | |
| Silver SCHEMBL502034 | 0.82 | — | — | |
| SCHEMBL442743 | 0.82 | — | — | |
| SCHEMBL93542 | 0.82 | — | — | |
| SCHEMBL1410012 | 0.82 | — | — | |
| SCHEMBL157767 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7419607-B2 | Structural component exposed to an aqueous environment adapted to retain or deliver fluid formed from a biofilm resistant polymer and a inorganic carrier conjugated with a biocidal metal ion; the delivered or retained fluid contains the biocidal metal ion to replenish exhausted ions | DOWNS BRADLEY | 2008-09-02 | — | — | US | claimed |
| US-20060180552-A1 | Anti-biofilm forming structure and method of manufacturing the same | DOWNS BRADLEY | 2006-08-17 | — | — | US | claimed |
| WO-2013128304-A1 | ENDOTRACHEAL TUBES AND OTHER POLYMER SUBSTRATES INCLUDING AN ANTI-FOULING TREATMENT | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2013-09-06 | — | — | WO | disclosed |
| US-20130220331-A1 | Endotracheal Tubes and Other Polymer Substrates Including An Anti-Fouling Treatment | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2013-08-29 | — | — | US | disclosed |
| US-20110117152-A1 | SILICONE RUBBER EXHIBITING EFFECTIVE ANTIMICROBIAL ACTIVITY | MOMENTIVE PERFORMANCE MATERIALS INC. | 2011-05-19 | — | — | US | disclosed |
| US-7845351-B2 | Germicidal face mask | KIMBERLY-CLARK WORLDWIDE INC. (US) | 2010-12-07 | — | — | US | disclosed |
| US-20080236598-A1 | Drape for open tracheal suctioning | KIMBERLY-CLARK WORLDWIDE, INC. | 2008-10-02 | — | — | US | disclosed |
| US-20070044801-A1 | Germicidal face mask | O&M HALYARD, INC. | 2007-03-01 | — | — | US | disclosed |
| US-20070048356-A1 | Antimicrobial treatment of nonwoven materials for infection control | KIMBERLY-CLARK WORLDWIDE, INC. | 2007-03-01 | — | — | US | disclosed |
| US-20060276339-A1 | Methods and compositions for increasing the efficacy of biologically-active ingredients | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2006-12-07 | — | — | US | disclosed |
| WO-2003099543-A1 | ANTIMICROBIAL FILM STRUCTURES FOR USE IN HVAC | PECHINEY EMBALLAGE FLEXIBLE EUROPE (FR) | 2003-12-04 | — | — | WO | disclosed |
| US-20030215589-A1 | Antimicrobial film structures for use in HVAC | PECHINEY EMBALLAGE FLEXIBLE EUROPE (FR) | 2003-11-20 | — | — | US | disclosed |