Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A2 | O15244 | 13/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.59 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL85956 | 1.00 | SLC22A2 (0.59) | SLC22A2CYP3A4TMEM97ABCG2 | |
| SCHEMBL86168 | 0.94 | SLC22A2 (0.59) | SLC22A2CYP3A4TMEM97ABCG2 | |
| SCHEMBL86258 | 0.93 | SLC22A2 (0.60) | SLC22A2CYP3A4TMEM97ABCG2 | |
| SCHEMBL82524 | 0.90 | SLC22A2 (0.58) | SLC22A2CYP3A4TMEM97ABCG2 | |
| SCHEMBL81750 | 0.90 | SLC22A2 (0.58) | SLC22A2CYP3A4TMEM97ABCG2 | |
| SCHEMBL18881126 | 0.89 | SLC22A2 (0.45) | SLC22A2CYP3A4TMEM97ABCG2 | |
| SCHEMBL86319 | 0.86 | SLC22A2 (0.66) | SLC22A2CYP3A4TMEM97ABCG2 | |
| SCHEMBL19056193 | 0.86 | SLC22A2 (0.68) | SLC22A2CYP3A4TMEM97ABCG2 | |
| SCHEMBL82092 | 0.86 | SLC22A2 (0.68) | SLC22A2CYP3A4TMEM97ABCG2 | |
| SCHEMBL19327628 | 0.86 | SLC22A2 (0.68) | SLC22A2CYP3A4TMEM97ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3284519-A1 | POLYCYCLIC CARBAMOYLPYRIDONE DERIVATIVE HAVING HIV INTEGRASE INHIBITORY ACTIVITY | VIIV Healthcare Company (US) | 2018-02-21 | — | — | EP | disclosed |
| EP-3187226-A1 | POLYCYCLIC CARBAMOYLPYRIDONE DERIVATIVE HAVING HIV INTEGRASE INHIBITORY ACTIVITY | VIIV Healthcare Company (US) | 2017-07-05 | — | — | EP | disclosed |
| EP-3187225-A1 | POLYCYCLIC CARBAMOYLPYRIDONE DERIVATIVE HAVING HIV INTEGRASE INHIBITORY ACTIVITY | VIIV Healthcare Company (US) | 2017-07-05 | — | — | EP | disclosed |