Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.53 |
| ▸ | HTR2B | P41595 | 5/20 | 0.53 |
| ▸ | HTR2A | P28223 | 4/20 | 0.53 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 6/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | ABCC9 | O60706 | 6/20 | 0.39 |
| ▸ | KCNJ11 | Q14654 | 6/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.38 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22334917 | 0.87 | KDM1A (0.60) | HTR2CHTR2BHTR2AKDM1AKCNH2 | |
| SCHEMBL23993624 | 0.84 | HTR2A (0.67) | HTR2CHTR2BHTR2AKDM1AKCNH2 | |
| SCHEMBL20202736 | 0.84 | HTR2A (0.67) | HTR2CHTR2BHTR2AKDM1AKCNH2 | |
| SCHEMBL23995530 | 0.80 | HTR2A (0.49) | HTR2CHTR2BHTR2AKDM1AKCNH2 | |
| SCHEMBL23995528 | 0.78 | HTR2C (0.47) | HTR2CHTR2BHTR2AKDM1ASLC6A4 | |
| SCHEMBL22335111 | 0.78 | HTR2C (0.46) | HTR2CHTR2BHTR2AKDM1AKCNH2 | |
| SCHEMBL23993627 | 0.77 | HTR2A (0.49) | HTR2CHTR2BHTR2AKDM1ASLC6A4 | |
| SCHEMBL21503512 | 0.74 | HTR2C (0.66) | HTR2CHTR2BHTR2AKDM1ASLC6A4 | |
| SCHEMBL22334928 | 0.74 | HTR2C (0.66) | HTR2CHTR2BHTR2AKDM1AKCNH2 | |
| SCHEMBL16590511 | 0.74 | HTR2C (0.66) | HTR2CHTR2BHTR2AKDM1ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2493845-A1 | SUBSTITUTED 3-PHENYLPROPIONIC ACIDS AND THE USE THEREOF | Bayer Pharma Aktiengesellschaft (DE) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011051165-A1 | SUBSTITUTED 3-PHENYLPROPIONIC ACIDS AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-05-05 | — | — | WO | disclosed |