⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28305777 | 0.64 | — | — | |
| SCHEMBL5431207 | 0.57 | — | — | |
| SCHEMBL21755790 | 0.57 | — | — | |
| SCHEMBL11676565 | 0.50 | — | — | |
| SCHEMBL19773623 | 0.50 | — | — | |
| SCHEMBL6639204 | 0.50 | — | — | |
| Butane SCHEMBL2594939 | 0.49 | — | — | |
| SCHEMBL20679047 | 0.45 | — | — | |
| SCHEMBL15951371 | 0.43 | — | — | |
| SCHEMBL620750 | 0.43 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192686-A1 | METHODS FOR PREVENTING OR SLOWING THE PROGRESSION OF COGNITIVE DECLINE OR IMPAIRMENT IN SUBJECTS DISPLAYING NORMAL COGNITIVE PERFORMANCE | Li shi jiang (US) | 2023-10-05 | — | — | WO | disclosed |
| WO-2022011318-A1 | COMBINATIONS OF GABAA ALPHA 5 AGONISTS AND SV2A INHIBITORS AND METHODS OF USING IN THE TREATMENT OF COGNITIVE IMPAIRMENT | AGENEBIO, INC. (US) | 2022-01-13 | — | — | WO | disclosed |
| WO-2021127543-A1 | BENZODIAZEPINE DERIVATIVES, COMPOSITIONS, AND METHODS FOR TREATING COGNITIVE IMPAIRMENT | AGENEBIO, INC. (US) | 2021-06-24 | — | — | WO | disclosed |
| EP-3272738-A2 | PROCESSES FOR PREPARING JAK INHIBITORS AND RELATED INTERMEDIATE COMPOUNDS | Incyte Holdings Corporation (US) | 2018-01-24 | — | — | EP | disclosed |
| EP-2398774-B1 | PROCESSES FOR PREPARING JAK INHIBITORS AND RELATED INTERMEDIATE COMPOUNDS | INCYTE HOLDINGS CORP (US) | 2017-07-05 | — | — | EP | disclosed |