Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.55 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.55 |
| ▸ | DRD4 | P21917 | 5/20 | 0.55 |
| ▸ | DRD2 | P14416 | 4/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.54 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.54 |
| ▸ | FAAH | O00519 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MC4R | P32245 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17294922 | 0.93 | S1PR1 (0.53) | S1PR1S1PR5SIGMAR1DRD4DRD2 | |
| SCHEMBL22399618 | 0.88 | FUCA1 (0.50) | S1PR1S1PR5SIGMAR1DRD4DRD2 | |
| SCHEMBL17961749 | 0.87 | DRD4 (0.70) | SIGMAR1DRD4DRD2DRD3KMT2A | |
| SCHEMBL20183285 | 0.87 | DRD4 (0.70) | SIGMAR1DRD4DRD2DRD3KMT2A | |
| SCHEMBL19614234 | 0.87 | DRD4 (0.70) | SIGMAR1DRD4DRD2DRD3KMT2A | |
| SCHEMBL12655772 | 0.87 | S1PR1 (0.53) | S1PR1S1PR5SIGMAR1DRD4DRD2 | |
| SCHEMBL25265214 | 0.87 | HRH4 (0.49) | S1PR1S1PR5SIGMAR1DRD4DRD2 | |
| SCHEMBL16653708 | 0.87 | HRH4 (0.49) | S1PR1S1PR5SIGMAR1DRD4DRD2 | |
| SCHEMBL15880136 | 0.87 | HRH4 (0.49) | S1PR1S1PR5SIGMAR1DRD4DRD2 | |
| SCHEMBL15914140 | 0.87 | HRH4 (0.49) | S1PR1S1PR5SIGMAR1DRD4DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117242060-A | Isoindolinone compounds | 蒙特罗萨医疗公司 | 2023-12-15 | — | — | CN | disclosed |
| WO-2011060397-A1 | SUBSTITUTED AMINO HETEROCYCLES USEFUL AS HIV ANTAGONISTS | SCHERING CORPORATION (US) | 2011-05-19 | — | — | WO | disclosed |