SCHEMBL1908266

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1900096	0.90	RET (0.46)	RETRAB9APGK1TTK
	SCHEMBL1907100	0.86	RET (0.43)	RETTTK
	SCHEMBL1904484	0.83	FLT1 (0.45)	RETGAAFYNPGK1TTK
	SCHEMBL1902793	0.82	FYN (0.47)	RETKDM4EALDH1A1GAAHPGD
	SCHEMBL1907765	0.82	PDE10A (0.49)	RETKDM4EMEN1ALDH1A1HPGD
	SCHEMBL1906720	0.82	PDE1A (0.42)	RETPGK1TTKCCNA2CDK2
	SCHEMBL2355401	0.80	RET (0.42)	RETTTKCCNA2CDK2
	SCHEMBL1906997	0.79	RET (0.51)	RET
	SCHEMBL2352858	0.79	RET (0.43)	RETMEN1ALDH1A1MAPTHPGD
	SCHEMBL12460675	0.77	RET (0.49)	RET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.