Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10253514 | 0.83 | DHODH (0.64) | DHODH | |
| SCHEMBL20482409 | 0.81 | DHODH (0.61) | DHODH | |
| SCHEMBL23951398 | 0.79 | DHODH (0.62) | DHODH | |
| SCHEMBL643678 | 0.78 | DHODH (0.64) | DHODH | |
| SCHEMBL29893957 | 0.78 | DHODH (0.64) | DHODH | |
| SCHEMBL2919366 | 0.77 | DHODH (0.57) | DHODH | |
| SCHEMBL19064517 | 0.77 | KDM4E (0.61) | DHODHHTT | |
| SCHEMBL21974417 | 0.77 | DHODH (0.97) | DHODH | |
| SCHEMBL20482589 | 0.76 | DHODH (0.84) | DHODH | |
| SCHEMBL20482586 | 0.76 | DHODH (1.00) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170190675-A1 | CHEMICAL MODULATORS OF IMMUNE CHECKPOINTS AND THERAPEUTIC USE | DUKE UNIVERSITY | 2017-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170190675-A1 | CHEMICAL MODULATORS OF IMMUNE CHECKPOINTS AND THERAPEUTIC USE | CD274, PDCD1, PDCD1LG2 | DHODH 2751/4885HTT 4191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.