Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 19/20 | 0.76 |
| ▸ | HTR2A | P28223 | 18/20 | 0.76 |
| ▸ | HTR2B | P41595 | 15/20 | 0.76 |
| ▸ | DRD1 | P21728 | 1/20 | 0.51 |
| ▸ | DRD5 | P21918 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1908444 | 1.00 | HTR2C (0.76) | HTR2CHTR2AHTR2BDRD1DRD5 | |
| SCHEMBL1094962 | 0.87 | HTR2C (1.00) | HTR2CHTR2AHTR2B | |
| SCHEMBL1094326 | 0.87 | HTR2C (1.00) | HTR2CHTR2AHTR2B | |
| SCHEMBL1094963 | 0.87 | HTR2C (1.00) | HTR2CHTR2AHTR2B | |
| SCHEMBL1095714 | 0.82 | HTR2C (0.71) | HTR2CHTR2AHTR2BDRD1DRD5 | |
| SCHEMBL1095210 | 0.82 | HTR2C (1.00) | HTR2CHTR2AHTR2BDRD1DRD5 | |
| SCHEMBL1095190 | 0.82 | HTR2C (1.00) | HTR2CHTR2AHTR2BDRD1DRD5 | |
| SCHEMBL1095713 | 0.82 | HTR2C (0.71) | HTR2CHTR2AHTR2BDRD1DRD5 | |
| SCHEMBL1095188 | 0.82 | HTR2C (1.00) | HTR2CHTR2AHTR2BDRD1DRD5 | |
| SCHEMBL1097007 | 0.82 | HTR2C (1.00) | HTR2CHTR2AHTR2BDRD1DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2322162-A1 | 5HT2C receptor modulator compositions and methods of use | Arena Pharmaceuticals, Inc. (US) | 2011-05-18 | — | — | EP | disclosed |