SCHEMBL19085443

SCHEMBL19085443

Cc1c(C=O)c(=O)oc2c(F)c(O)c(F)cc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.41
GAA P10253 7/20 0.41
HPGD P15428 7/20 0.41
ALDH1A1 P00352 6/20 0.41
MAPT P10636 3/20 0.41
LMNA P02545 3/20 0.41
POLB P06746 2/20 0.41
MAPK1 P28482 2/20 0.41
BLM P54132 2/20 0.41
HTT P42858 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
NSD2 O96028 1/20 0.41
CASP6 P55212 1/20 0.41
ESR2 Q92731 4/20 0.40
ESR1 P03372 3/20 0.40
CNR2 P34972 3/20 0.40
GPR55 Q9Y2T6 3/20 0.40
HSD17B3 P37058 1/20 0.38
ERN1 O75460 1/20 0.38
NUAK1 O60285 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13177605 0.85 KDM4E (0.48) KDM4EGAAHPGDALDH1A1MAPT
SCHEMBL23395072 0.80 KDM4E (0.42) KDM4EGAAHPGDALDH1A1MAPT
SCHEMBL17716549 0.79 KDM4E (0.66) KDM4EGAAHPGDALDH1A1MAPT
SCHEMBL14924891 0.78 KDM4E (0.59) KDM4EGAAHPGDALDH1A1MAPT
SCHEMBL22702331 0.77 KDM4E (0.41) KDM4EGAAHPGDALDH1A1MAPT
SCHEMBL16645386 0.77 KDM4E (0.56) KDM4EGAAHPGDALDH1A1MAPT
SCHEMBL17716514 0.77 KDM4E (0.41) KDM4EGAAHPGDALDH1A1MAPT
SCHEMBL8568000 0.77 KDM4E (0.41) KDM4EGAAHPGDALDH1A1MAPT
SCHEMBL18807744 0.76 KDM4E (0.43) KDM4EGAAHPGDALDH1A1MAPT
SCHEMBL10026038 0.75 KDM4E (0.43) KDM4EGAAHPGDALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017114877-A1 FLUORESCENT PARTICULATE MATERIAL L'OREAL (FR) 2017-07-06 WO disclosed