Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 20/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19086084 | 0.91 | LRRK2 (0.58) | LRRK2 | |
| SCHEMBL19086085 | 0.90 | LRRK2 (0.59) | LRRK2 | |
| SCHEMBL19086089 | 0.89 | LRRK2 (0.60) | LRRK2 | |
| SCHEMBL19086096 | 0.88 | LRRK2 (0.57) | LRRK2 | |
| SCHEMBL19086088 | 0.83 | LRRK2 (0.58) | LRRK2 | |
| SCHEMBL15864770 | 0.75 | LRRK2 (0.65) | LRRK2 | |
| SCHEMBL15864659 | 0.73 | LRRK2 (1.00) | LRRK2 | |
| SCHEMBL15865251 | 0.72 | LRRK2 (1.00) | LRRK2 | |
| SCHEMBL15865076 | 0.72 | LRRK2 (0.73) | LRRK2 | |
| SCHEMBL28112547 | 0.71 | LRRK2 (0.63) | LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2941425-B1 | AMINOPYRIDINE DERIVED COMPOUNDS AS LRRK2 INHIBITORS | H LUNDBECK AS (DK) | 2017-07-12 | — | — | EP | claimed |