Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 10/20 | 0.49 |
| ▸ | SRC | P12931 | 8/20 | 0.49 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.49 |
| ▸ | PRKDC | P78527 | 7/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.49 |
| ▸ | PIK3CB | P42338 | 6/20 | 0.49 |
| ▸ | EGFR | P00533 | 4/20 | 0.49 |
| ▸ | ABL1 | P00519 | 3/20 | 0.49 |
| ▸ | HCK | P08631 | 2/20 | 0.49 |
| ▸ | KDR | P35968 | 2/20 | 0.49 |
| ▸ | MTOR | P42345 | 2/20 | 0.49 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.49 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.49 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | ABL2 | P42684 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 2/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11231 | 0.92 | PIK3CD (0.50) | PIK3CDSRCPIK3CGPRKDCPIK3CA | |
| SCHEMBL29651706 | 0.92 | PIK3CD (0.50) | PIK3CDSRCPIK3CGPRKDCPIK3CA | |
| SCHEMBL26963102 | 0.87 | PIK3CD (0.53) | PIK3CDSRCPIK3CGPRKDCPIK3CA | |
| SCHEMBL26963103 | 0.86 | PIK3CD (0.49) | PIK3CDSRCPIK3CGPIK3R1BTK | |
| SCHEMBL11383 | 0.85 | PIK3CD (0.54) | PIK3CDSRCPIK3CGPRKDCPIK3CA | |
| SCHEMBL30013119 | 0.85 | PIK3CD (0.54) | PIK3CDSRCPIK3CGPRKDCPIK3CA | |
| SCHEMBL29651700 | 0.83 | PIK3CD (0.49) | PIK3CDSRCPIK3CGPRKDCPIK3CA | |
| SCHEMBL10948 | 0.83 | PIK3CD (0.49) | PIK3CDSRCPIK3CGPRKDCPIK3CA | |
| SCHEMBL131150 | 0.81 | SRC (0.48) | PIK3CDSRCPIK3CGPRKDCPIK3CA | |
| SCHEMBL11097 | 0.81 | BTK (0.49) | PIK3CDSRCPIK3CGPRKDCPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2496567-B1 | NOVEL BENZOPYRAN KINASE MODULATORS | RHIZEN PHARMACEUTICALS S A (CH) | 2017-07-12 | — | — | EP | claimed |