Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 18/20 | 0.50 |
| ▸ | PIK3CG | P48736 | 8/20 | 0.45 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.45 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 6/20 | 0.40 |
| ▸ | PRKDC | P78527 | 3/20 | 0.40 |
| ▸ | SRC | P12931 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | HCK | P08631 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29651699 | 0.93 | PIK3CD (0.51) | PIK3CDPIK3CGPIK3R1CSNK1EPIK3CA | |
| SCHEMBL10943 | 0.93 | PIK3CD (0.51) | PIK3CDPIK3CGPIK3R1CSNK1EPIK3CA | |
| SCHEMBL29651581 | 0.86 | PIK3CD (0.44) | PIK3CDPIK3CGPIK3CAPIK3CBPRKDC | |
| SCHEMBL11009 | 0.86 | PIK3CD (0.44) | PIK3CDPIK3CGPIK3CAPIK3CBPRKDC | |
| SCHEMBL29651698 | 0.86 | PIK3CD (0.45) | PIK3CDPIK3CGPIK3R1CSNK1EPIK3CA | |
| SCHEMBL10432 | 0.86 | PIK3CD (0.45) | PIK3CDPIK3CGPIK3R1CSNK1EPIK3CA | |
| SCHEMBL26963102 | 0.85 | PIK3CD (0.53) | PIK3CDPIK3CGPIK3R1CSNK1EPIK3CA | |
| SCHEMBL131081 | 0.83 | PIK3CD (0.72) | PIK3CDPIK3CGPIK3R1CSNK1EPIK3CA | |
| SCHEMBL15582861 | 0.83 | PIK3CD (0.72) | PIK3CDPIK3CGPIK3R1CSNK1EPIK3CA | |
| SCHEMBL29651637 | 0.83 | PIK3CD (0.72) | PIK3CDPIK3CGPIK3R1CSNK1EPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2496567-B1 | NOVEL BENZOPYRAN KINASE MODULATORS | RHIZEN PHARMACEUTICALS S A (CH) | 2017-07-12 | — | — | EP | claimed |