Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2B6 | P20813 | 1/20 | 0.58 |
| ▸ | TENT4A | Q5XG87 | 1/20 | 0.58 |
| ▸ | TENT4B | Q8NDF8 | 1/20 | 0.58 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19087171 | 1.00 | CYP2B6 (0.58) | CYP2B6TENT4ATENT4BACHEOPRM1 | |
| SCHEMBL16981066 | 0.98 | CYP2B6 (0.56) | CYP2B6TENT4ATENT4BACHEOPRM1 | |
| SCHEMBL16981173 | 0.91 | CYP2B6 (0.58) | CYP2B6TENT4ATENT4B | |
| SCHEMBL16981290 | 0.91 | CYP2B6 (0.48) | CYP2B6TENT4ATENT4B | |
| SCHEMBL16981018 | 0.91 | CYP2B6 (0.47) | CYP2B6TENT4ATENT4BACHE | |
| SCHEMBL16981188 | 0.91 | CYP2B6 (0.47) | CYP2B6TENT4ATENT4BACHE | |
| SCHEMBL16981155 | 0.90 | CYP2B6 (0.57) | CYP2B6TENT4ATENT4B | |
| SCHEMBL16981028 | 0.90 | CYP2B6 (0.57) | CYP2B6TENT4ATENT4B | |
| SCHEMBL26713996 | 0.90 | CYP2B6 (0.57) | CYP2B6TENT4ATENT4B | |
| SCHEMBL21043355 | 0.90 | CYP2B6 (0.71) | CYP2B6TENT4ATENT4BACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017114812-A1 | COMBINATION THERAPY OF AN HBSAG INHIBITOR AND AN INTERFERON | F. HOFFMANN-LA ROCHE AG (CH) | 2017-07-06 | — | — | WO | disclosed |