Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18256541 | 0.88 | NPC1 (0.51) | NPC1HPGDRAB9ASMN1; SMN2TSHR | |
| SCHEMBL29540939 | 0.88 | NPC1 (0.51) | NPC1HPGDRAB9ASMN1; SMN2TSHR | |
| SCHEMBL24093766 | 0.80 | KMT2A (0.46) | NPC1HPGDRAB9ASMN1; SMN2TSHR | |
| SCHEMBL29541462 | 0.79 | HPGD (0.50) | NPC1HPGDRAB9ASMN1; SMN2TSHR | |
| SCHEMBL18256539 | 0.79 | HPGD (0.50) | NPC1HPGDRAB9ASMN1; SMN2TSHR | |
| SCHEMBL23279498 | 0.78 | KDM4E (0.47) | HPGDTSHRKMT2AMEN1NPSR1 | |
| SCHEMBL26028564 | 0.77 | HPGD (0.46) | NPC1HPGDRAB9ASMN1; SMN2TSHR | |
| SCHEMBL8252614 | 0.77 | NPC1 (0.50) | NPC1HPGDRAB9ASMN1; SMN2TSHR | |
| SCHEMBL30771563 | 0.77 | NPC1 (0.61) | NPC1HPGDRAB9ASMN1; SMN2TSHR | |
| SCHEMBL2152084 | 0.77 | NPC1 (0.61) | NPC1HPGDRAB9ASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3922639-A1 | ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS | Boehringer Ingelheim Animal Health USA Inc. (US) | 2021-12-15 | — | — | EP | disclosed |
| EP-3298027-B1 | ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2021-04-28 | — | — | EP | disclosed |
| WO-2017116702-A1 | ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS | MERIAL, INC. (US) | 2017-07-06 | — | — | WO | disclosed |