Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.58 |
| ▸ | IGF1R | P08069 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20548888 | 0.93 | EGFR (0.68) | EGFRIGF1RKCNH2 | |
| SCHEMBL19089298 | 0.92 | EGFR (0.59) | EGFRIGF1RKCNH2 | |
| SCHEMBL20548840 | 0.92 | EGFR (0.59) | EGFRIGF1RKCNH2 | |
| SCHEMBL20548844 | 0.91 | EGFR (0.60) | EGFRIGF1RKCNH2 | |
| SCHEMBL19089293 | 0.91 | EGFR (0.67) | EGFR | |
| SCHEMBL19089295 | 0.91 | EGFR (0.65) | EGFRIGF1RKCNH2 | |
| SCHEMBL20548762 | 0.90 | EGFR (0.56) | EGFR | |
| SCHEMBL19089370 | 0.89 | EGFR (0.61) | EGFRIGF1RKCNH2 | |
| SCHEMBL20548768 | 0.89 | EGFR (0.61) | EGFRIGF1RKCNH2 | |
| SCHEMBL19089368 | 0.88 | EGFR (0.61) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017114500-A1 | ACRYLANILIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATIONS THEREOF IN PHARMACY | 恩瑞生物医药科技（上海）有限公司 | 2017-07-06 | — | — | WO | disclosed |