Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 19/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.44 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.44 |
| ▸ | IGF1R | P08069 | 1/20 | 0.43 |
| ▸ | EML4 | Q9HC35 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19089291 | 0.88 | EGFR (0.47) | EGFRERBB2ALKIGF1REML4 | |
| SCHEMBL19089463 | 0.87 | EGFR (0.47) | EGFRERBB2IGF1R | |
| SCHEMBL35210301 | 0.84 | EGFR (0.45) | EGFRERBB2IGF1R | |
| SCHEMBL19089290 | 0.84 | EGFR (0.66) | EGFRALKEML4 | |
| SCHEMBL19089465 | 0.81 | EGFR (0.48) | EGFRALKEML4 | |
| SCHEMBL17384818 | 0.81 | EGFR (0.70) | EGFRERBB2ALKEML4 | |
| SCHEMBL29855954 | 0.81 | EGFR (0.54) | EGFRALKEML4 | |
| SCHEMBL20655389 | 0.80 | EGFR (0.45) | EGFRERBB2IGF1R | |
| SCHEMBL22520229 | 0.80 | EGFR (0.54) | EGFRALKEML4 | |
| SCHEMBL19089584 | 0.79 | EGFR (0.52) | EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017114500-A1 | ACRYLANILIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATIONS THEREOF IN PHARMACY | 恩瑞生物医药科技（上海）有限公司 | 2017-07-06 | — | — | WO | disclosed |