Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.51 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.43 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.43 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL35210280 | 0.92 | EGFR (0.61) | EGFRALKEML4 | |
| SCHEMBL20548739 | 0.92 | EGFR (0.61) | EGFRALKEML4 | |
| SCHEMBL20548764 | 0.84 | EGFR (0.61) | EGFRALKEML4 | |
| SCHEMBL35210263 | 0.84 | EGFR (0.61) | EGFRALKEML4 | |
| SCHEMBL19089565 | 0.83 | EGFR (0.48) | EGFRALKEML4 | |
| SCHEMBL20548738 | 0.82 | EGFR (0.49) | EGFRALKEML4 | |
| SCHEMBL20656035 | 0.81 | EGFR (0.48) | EGFRALKERBB3 | |
| SCHEMBL19089677 | 0.81 | EGFR (0.63) | EGFRALKEML4 | |
| SCHEMBL19089672 | 0.81 | EGFR (0.57) | EGFRALKEML4 | |
| SCHEMBL35210283 | 0.81 | EGFR (0.57) | EGFRALKEML4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017114500-A1 | ACRYLANILIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATIONS THEREOF IN PHARMACY | 恩瑞生物医药科技（上海）有限公司 | 2017-07-06 | — | — | WO | disclosed |