Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19091547 | 0.87 | GAA (0.47) | GAACTSDBTKNFKB1NFKB2 | |
| SCHEMBL19091093 | 0.85 | GAA (0.42) | GAACTSDBTKNAAANFKB1 | |
| SCHEMBL19091089 | 0.82 | GAA (0.43) | GAACTSDBTKNAAANFKB1 | |
| SCHEMBL19091107 | 0.82 | GAA (0.43) | GAACTSDBTKNAAANFKB1 | |
| SCHEMBL19091088 | 0.82 | GAA (0.49) | GAACTSDBTKNAAANFKB1 | |
| SCHEMBL19091112 | 0.81 | GAA (0.42) | GAACTSDBTKNAAANFKB1 | |
| SCHEMBL19091636 | 0.81 | GAA (0.41) | GAACTSDBTKNFKB1NFKB2 | |
| SCHEMBL19091090 | 0.81 | GAA (0.41) | GAANFKB1NFKB2RELAKMT2A | |
| SCHEMBL19091499 | 0.81 | GAA (0.41) | GAACTSDNAAA | |
| SCHEMBL19091637 | 0.81 | GAA (0.41) | GAACTSDBTKNAAANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017116954-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2017-07-06 | — | — | WO | disclosed |