SCHEMBL19095705

SCHEMBL19095705

Cc1ccc(-c2ccc(-c3cc(F)c(OCc4cc(F)c(F)c(F)c4)c(F)c3)c(F)c2)cc1

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.38
FFAR4 Q5NUL3 7/20 0.38
FFAR1 O14842 3/20 0.34
CNR1 P21554 1/20 0.34
PDE3B Q13370 1/20 0.33
PDE3A Q14432 1/20 0.33
F10 P00742 1/20 0.33
THRA P10827 1/20 0.33
THRB P10828 1/20 0.33
RPS6KA3 P51812 2/20 0.32
ALOX5AP P20292 1/20 0.32
FEN1 P39748 1/20 0.32
ANO1 Q5XXA6 1/20 0.32
PTGES2 Q9H7Z7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19098113 0.92 MAOB (0.40) MAOBFFAR4FFAR1THRATHRB
SCHEMBL19703010 0.90 MAOB (0.42) MAOBFFAR4FFAR1CNR1F10
SCHEMBL19098120 0.90 MAOB (0.42) MAOBFFAR4FFAR1CNR1F10
SCHEMBL19098124 0.89 FFAR4 (0.38) MAOBFFAR4FFAR1F10THRA
SCHEMBL19082866 0.88 FFAR4 (0.38) MAOBFFAR4FFAR1F10FEN1
SCHEMBL20936066 0.88 FFAR4 (0.41) MAOBFFAR4FFAR1F10ALOX5AP
SCHEMBL19098117 0.86 FFAR4 (0.36) MAOBFFAR4FFAR1CNR1ALOX5AP
SCHEMBL19097709 0.86 MAOB (0.37) MAOBFFAR4FFAR1ALOX5APFEN1
SCHEMBL16038268 0.86 RARB (0.37) MAOBFFAR4FFAR1F10
SCHEMBL19098125 0.85 FFAR4 (0.37) MAOBFFAR4FFAR1CNR1F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9994772-B2 Liquid crystal display device DIC CORPORATION (JP) 2018-06-12 US disclosed
US-20180148647-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY USING SAME DIC CORPORATION (JP) 2018-05-31 US disclosed
US-20170190972-A1 LIQUID CRYSTAL DISPLAY DEVICE SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2017-07-06 US disclosed