Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 7/20 | 0.47 |
| ▸ | DYRK1B | Q9Y463 | 5/20 | 0.47 |
| ▸ | DYRK2 | Q92630 | 3/20 | 0.47 |
| ▸ | PRKCI | P41743 | 1/20 | 0.42 |
| ▸ | CLK1 | P49759 | 3/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | CLK2 | P49760 | 1/20 | 0.40 |
| ▸ | CLK3 | P49761 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | GPR183 | P32249 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21933249 | 0.77 | CYP19A1 (0.66) | MAPTRAB9ASMN1; SMN2CYP19A1 | |
| SCHEMBL17821835 | 0.74 | DYRK1A (0.54) | DYRK1ADYRK1BDYRK2PRKCICLK1 | |
| SCHEMBL15965547 | 0.74 | DYRK1A (0.54) | DYRK1ADYRK1BDYRK2PRKCICLK1 | |
| SCHEMBL17821837 | 0.74 | DYRK1A (0.54) | DYRK1ADYRK1BDYRK2PRKCICLK1 | |
| SCHEMBL11981321 | 0.74 | CYP3A4 (0.56) | DYRK1ADYRK1BDYRK2PRKCICLK1 | |
| SCHEMBL19097994 | 0.74 | NPC1 (0.44) | DYRK1ADYRK1BDYRK2ERN1PIK3CA | |
| SCHEMBL19805778 | 0.73 | KDM4E (0.53) | DYRK1ADYRK1BDYRK2PRKCICLK1 | |
| SCHEMBL16178877 | 0.72 | DYRK1A (0.41) | DYRK1ADYRK1BDYRK2PRKCIERN1 | |
| SCHEMBL1647020 | 0.72 | DYRK1A (0.55) | DYRK1ADYRK1BDYRK2PRKCICLK1 | |
| SCHEMBL29585187 | 0.72 | DYRK1A (0.55) | DYRK1ADYRK1BDYRK2PRKCICLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017113964-A1 | NOVEL STILBENE DERIVATIVE AND PREPARATION METHOD THEREOF | 北京理工大学 | 2017-07-06 | — | — | WO | disclosed |