Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 3/20 | 0.51 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19063783 | 1.00 | GBA1 (0.51) | GBA1S1PR5S1PR1FUCA1OPRM1 | |
| SCHEMBL3617880 | 0.79 | S1PR5 (0.47) | S1PR5S1PR1FUCA1OPRM1ACHE | |
| SCHEMBL2692741 | 0.79 | S1PR5 (0.47) | S1PR5S1PR1FUCA1OPRM1ACHE | |
| SCHEMBL2692744 | 0.79 | S1PR5 (0.47) | S1PR5S1PR1FUCA1OPRM1ACHE | |
| SCHEMBL2692748 | 0.79 | S1PR5 (0.47) | S1PR5S1PR1FUCA1OPRM1ACHE | |
| SCHEMBL66496 | 0.78 | BRD4 (0.43) | S1PR5S1PR1FUCA1OPRM1ACHE | |
| SCHEMBL5652849 | 0.78 | BRD4 (0.43) | S1PR5S1PR1FUCA1OPRM1ACHE | |
| SCHEMBL3527474 | 0.77 | GRIN2B (0.45) | S1PR5S1PR1FUCA1OPRM1ACHE | |
| SCHEMBL15012080 | 0.77 | BCHE (0.48) | FUCA1OPRM1ACHEBCHEKDM4E | |
| SCHEMBL15012081 | 0.77 | BCHE (0.48) | FUCA1OPRM1ACHEBCHEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3400228-A1 | FUSED QUADRACYCLIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | Tabomedex Biosciences, LLC (US) | 2018-11-14 | — | — | EP | disclosed |
| WO-2017120164-A1 | FUSED QUADRACYCLIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | Tabomedex Biosciences, LLC (US) | 2017-07-13 | — | — | WO | disclosed |