Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 5/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19101784 | 0.89 | TMPRSS2 (0.43) | TMPRSS2NPC1ALDH1A1ATMTDP1 | |
| SCHEMBL16708527 | 0.87 | TMPRSS2 (0.39) | TMPRSS2NPC1ALDH1A1ATMTDP1 | |
| SCHEMBL19101882 | 0.86 | TMPRSS2 (0.43) | TMPRSS2NPC1ALDH1A1ATMTDP1 | |
| SCHEMBL16708481 | 0.85 | TMPRSS2 (0.41) | TMPRSS2NPC1ALDH1A1ATMTDP1 | |
| SCHEMBL19101807 | 0.85 | TMPRSS2 (0.48) | TMPRSS2NPC1ALDH1A1ATMTDP1 | |
| SCHEMBL19101759 | 0.85 | TMPRSS2 (0.41) | TMPRSS2NPC1ALDH1A1ATMTDP1 | |
| SCHEMBL16708484 | 0.85 | TMPRSS2 (0.42) | TMPRSS2NPC1ALDH1A1ATMTDP1 | |
| SCHEMBL19102179 | 0.84 | TMPRSS2 (0.44) | TMPRSS2NPC1ALDH1A1ATMTDP1 | |
| SCHEMBL16708490 | 0.82 | TMPRSS2 (0.39) | TMPRSS2NPC1ALDH1A1ATMTDP1 | |
| SCHEMBL16708486 | 0.80 | TMPRSS2 (0.38) | TMPRSS2NPC1ALDH1A1ATMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701682-B2 | Pyrrolo[1,2-f][1,2,4]triazines useful for treating respiratory syncitial virus infections | GILEAD SCIENCES, INC. (US) | 2017-07-11 | — | — | US | disclosed |