Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL107333 | 0.76 | MGAM (0.38) | ALDH1A1TDP1MGAMGAASI | |
| SCHEMBL29169988 | 0.72 | MGAM (0.35) | ALDH1A1TDP1MGAMGAASI | |
| SCHEMBL246813 | 0.72 | TSHR (0.52) | ALDH1A1TDP1 | |
| SCHEMBL8866823 | 0.70 | CTSA (0.39) | ALDH1A1TDP1 | |
| SCHEMBL2988766 | 0.70 | — | — | |
| SCHEMBL2994532 | 0.69 | MEN1 (0.35) | ALDH1A1TDP1 | |
| SCHEMBL2994665 | 0.66 | HTT (0.34) | — | |
| SCHEMBL16409731 | 0.66 | — | — | |
| SCHEMBL2879352 | 0.66 | TSHR (0.32) | — | |
| SCHEMBL17355671 | 0.66 | CYP3A4 (0.52) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701630-B2 | Difluorolactam compositions for EP4-mediated osteo related diseases and conditions | CAYMAN CHEMICAL COMPANY, INC. (US) | 2017-07-11 | — | — | US | disclosed |