Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | P4HB | P07237 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18100454 | 0.94 | MEN1 (0.37) | MEN1KMT2ACYP2C9CYP3A4DHODH | |
| SCHEMBL17451824 | 0.94 | MEN1 (0.37) | MEN1KMT2ACYP2C9CYP3A4DHODH | |
| SCHEMBL17435696 | 0.94 | MEN1 (0.37) | MEN1KMT2ACYP2C9CYP3A4DHODH | |
| SCHEMBL17435694 | 0.94 | MEN1 (0.37) | MEN1KMT2ACYP2C9CYP3A4DHODH | |
| SCHEMBL17435512 | 0.94 | MEN1 (0.37) | MEN1KMT2ACYP2C9CYP3A4DHODH | |
| SCHEMBL19102775 | 0.91 | DHODH (0.45) | CYP2C9DHODHALDH1A1GAALMNA | |
| SCHEMBL19102707 | 0.87 | MEN1 (0.38) | MEN1KMT2ACYP2C9CYP3A4DHODH | |
| SCHEMBL19102708 | 0.85 | ACACB (0.38) | MEN1KMT2ACYP2C9CYP3A4DHODH | |
| SCHEMBL17453185 | 0.84 | DHODH (0.43) | CYP2C9DHODHALDH1A1GAALMNA | |
| SCHEMBL17451844 | 0.84 | DHODH (0.43) | CYP2C9DHODHALDH1A1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701622-B2 | Antibacterial agents | ACHAOGEN, INC. (US) | 2017-07-11 | — | — | US | disclosed |