Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 2/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17453196 | 1.00 | ACACB (0.32) | ACACBL3MBTL1ALDH1A1P2RY6MMP13 | |
| SCHEMBL18100460 | 1.00 | ACACB (0.32) | ACACBL3MBTL1ALDH1A1P2RY6MMP13 | |
| SCHEMBL17451853 | 1.00 | ACACB (0.32) | ACACBL3MBTL1ALDH1A1P2RY6MMP13 | |
| SCHEMBL19102823 | 0.93 | ACACB (0.33) | ACACBL3MBTL1ALDH1A1P2RY6MMP13 | |
| SCHEMBL17435539 | 0.89 | — | — | |
| SCHEMBL17451855 | 0.89 | — | — | |
| SCHEMBL17451852 | 0.89 | — | — | |
| SCHEMBL17435538 | 0.89 | — | — | |
| SCHEMBL17435540 | 0.89 | — | — | |
| SCHEMBL17451826 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701622-B2 | Antibacterial agents | ACHAOGEN, INC. (US) | 2017-07-11 | — | — | US | disclosed |