Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19094399 | 0.89 | KCNH2 (0.47) | KCNH2 | |
| SCHEMBL11999992 | 0.84 | KCNH2 (0.48) | KCNH2 | |
| SCHEMBL19118599 | 0.84 | KCNH2 (0.43) | HRH2HRH1KCNH2 | |
| SCHEMBL707415 | 0.83 | KCNH2 (0.61) | KCNH2 | |
| SCHEMBL19094022 | 0.83 | KCNH2 (0.49) | KCNH2 | |
| SCHEMBL706071 | 0.82 | KCNH2 (0.52) | KCNH2 | |
| SCHEMBL19094093 | 0.82 | KCNH2 (0.44) | KCNH2 | |
| SCHEMBL19094362 | 0.82 | KCNH2 (0.40) | KCNH2 | |
| Hydrochloric Acid SCHEMBL2798199 | 0.82 | KCNH2 (0.60) | KCNH2 | |
| Hydrochloric Acid SCHEMBL3860901 | 0.81 | KCNH2 (0.51) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170197935-A1 | INHIBITORS OF DNA GYRASE FOR THE TREATMENT OF BACTERIAL INFECTIONS | VITAS PHARMA RESEARCH PRIVATE LIMITED (IN) | 2017-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170197935-A1 | INHIBITORS OF DNA GYRASE FOR THE TREATMENT OF BACTERIAL INFECTIONS | TOP1, TOP2A, DNASE1 | HRH2 1168/4885HRH1 1357/4885KCNH2 4625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.