Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM3 | Q86V86 | 20/20 | 0.69 |
| ▸ | PIM1 | P11309 | 19/20 | 0.69 |
| ▸ | PIM2 | Q9P1W9 | 19/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1910937 | 0.89 | PIM1 (0.65) | PIM3PIM1PIM2 | |
| SCHEMBL10278430 | 0.88 | PIM1 (0.62) | PIM3PIM1PIM2 | |
| SCHEMBL10278425 | 0.87 | PIM1 (0.68) | PIM3PIM1PIM2 | |
| SCHEMBL10278869 | 0.87 | PIM1 (0.68) | PIM3PIM1PIM2 | |
| SCHEMBL1910894 | 0.84 | PIM3 (0.71) | PIM3PIM1PIM2 | |
| SCHEMBL3224188 | 0.82 | PIM3 (1.00) | PIM3PIM1PIM2 | |
| SCHEMBL9608919 | 0.82 | PIM3 (1.00) | PIM3PIM1PIM2 | |
| SCHEMBL14906202 | 0.81 | PIM3 (0.64) | PIM3PIM1PIM2 | |
| SCHEMBL10278518 | 0.81 | PIM1 (0.69) | PIM3PIM1PIM2 | |
| SCHEMBL1911229 | 0.81 | PIM1 (0.69) | PIM3PIM1PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004217-A1 | CYCLIC ETHER COMPOUNDS USEFUL AS KINASE INHIBITORS | NOVARTIS AG (CH) | 2012-01-12 | — | — | WO | disclosed |